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Pharmaceutical-Grade Bismuth Subgallate Powder (CAS 99-26-3) - Astringent and Hemostatic Ingredient for Hemorrhoid Treatment
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Pharmaceutical-Grade Bismuth Subgallate Powder (CAS 99-26-3) - Astringent and Hemostatic Ingredient for Hemorrhoid Treatment
| MOQ: | 500g, 1kg or 25kg for sample, 1000kg for commercial order |
| Standard Packaging: | Net Weight 25kg or 200kg/package |
| Delivery Period: | In 3 working days |
| Payment Method: | T/T,LC,OA |
| Supply Capacity: | 3000 Tons/month |
Detail Information
Place of Origin
Shanxi, China
Brand Name
Zorui
Certification
ISO, COA, MSDS, TDS, AAA
Model Number
99-26-3
Product Name:
Bismuth Subgallate
CAS:
99-26-3
Sample:
Available
Port:
Tianjin, Shanghai, Qingdao, Other Ports In China
Trade Term:
EXW, DAP, FOB, CFR, CIF, CPT, CIP
Shipping:
Sample By Express, 100kg+ By Air, 1000kg+ By Sea
Storage:
Cool, Dry, And Well-ventilated Area; Avoid Moisture And High Heat
Highlight:
Pharmaceutical-Grade Bismuth Subgallate
,Astringent Bismuth Subgallate Powder
,Hemostatic CAS 99-26-3
Product Description
Bismuth Subgallate Powder (CAS 99-26-3) Hemorrhoid Treatment Ingredient
Bismuth Subgallate (CAS 99-26-3) is a pharmaceutical-grade complex of bismuth and gallic acid, renowned for its astringent, antiseptic, and hemostatic properties. This odorless, bright yellow powder is insoluble in water, making it ideal for gastrointestinal medications, wound care, and dermatological formulations. Compliant with USP/EP standards, it offers safe, effective management of skin irritation, minor bleeding, and digestive disorders.
Physical and Chemical Specifications
| Property | Specification |
|---|---|
| CAS Number | 99-26-3 |
| Molecular Formula | C7H5BiO6 |
| Appearance | Bright yellow amorphous powder |
| Bismuth Content | 46-52% (w/w) |
| Solubility | Insoluble in water, ethanol; soluble in dilute acids/alkalies |
| Loss on Drying | ≤ 1.0% |
| Heavy Metals (Pb) | ≤ 20 ppm |
| Storage | 15-25°C (protected from light) |
Product Functions
- Astringent: Contracts tissues to reduce secretions/bleeding
- Antiseptic: Mild antimicrobial action against skin pathogens
- Hemostatic: Promotes clot formation in minor wounds
- Gastroprotective: Forms protective coating in GI tract
- Radiopacity: Enhances visibility in X-ray diagnostics
Application Areas
- Pharmaceuticals: Ointments/powders for hemorrhoids, ulcers, and skin irritation; GI medications (anti-diarrheal, gastritis relief)
- Medical Devices: Radiopaque marker in surgical dressings
- Cosmetics: Soothing agent in diaper rash creams
- Veterinary: Topical wound management for animals
Manufacturing Process
- Reaction: Gallic acid reacts with bismuth nitrate in aqueous solution
- Precipitation: Alkaline pH adjustment to form insoluble Bismuth Subgallate
- Purification: Washing to remove nitrates and residual solvents
- Drying: Vacuum drying at ≤60°C to preserve stability
- Milling: Sieving to uniform particle size (90% < 100µm)
Why Choose Us
- Pharma-Grade Purity: >99% assay; USP/EP/JP compliance
- Low Toxicity: Meets ICH Q3D guidelines for elemental impurities
- Customization: Particle size (10-200µm), sterile options (gamma-irradiated)
- Certifications: GMP, ISO 9001, REACH, Halal/Kosher upon request
- Supply Chain: Batch traceability, 24-month shelf life, cold-chain shipping
Frequently Asked Questions
Is Bismuth Subgallate safe for open wounds?
Yes, it's USP-monographed for topical hemostasis and wound protection.
Why does stool turn black after ingestion?
Normal reaction - bismuth forms black sulfide in GI tract (harmless).
Can it replace bismuth subsalicylate (Pepto-Bismol ®)?
Similar GI benefits but without salicylates (safer for aspirin-sensitive patients).
Shelf life and storage?
24 months unopened; store below 25°C away from light/moisture.
Is it vegan-friendly?
Gallic acid is plant-derived (tannins), but confirm sourcing for strict vegan needs.
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