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High-Purity Zinc PCA (Zinc Pyrrolidone Carboxylic Acid) 98%+ for Sebum Regulation and Anti-acne in Cosmetics
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High-Purity Zinc PCA (Zinc Pyrrolidone Carboxylic Acid) 98%+ for Sebum Regulation and Anti-acne in Cosmetics
| MOQ: | 500 g, 1 kg o 25 kg para muestra, 1000 kg para pedido comercial |
| Embalaje Estándar: | Peso neto 25 kg o 200 kg/paquete |
| Período De Entrega: | en 3 días laborables |
| Método De Pago: | T/T,LC,OA |
| Capacidad De Suministro: | 3000 toneladas/mes |
Información detallada
Lugar de origen
Shanxi, China
Nombre de la marca
Zorui
Certificación
ISO, COA, MSDS, TDS, AAA
Número de modelo
15454-75-8
Nombre del producto:
Ácido carboxílico de pirrolidona de zinc (Zinc PCA)
CAS:
15454-75-8
Muestra:
Disponible
Puerto:
Tianjin, Shanghai, Qingdao, otros puertos de China
Término comercial:
EXW, DAP, MANDO, CFR, CIF, CPT, CIP
Envío:
Muestra por expreso, 100 kg+ por aire, 1000 kg+ por mar
Almacenamiento:
Área fresca, seca y bien ventilada; evitar la humedad y el calor alto
Descripción de producto
CAS 15454-75-8 High-Quality Zinc Pyrrolidone Carboxylic Acid (Zinc PCA) 98%+ Purity for Cosmetics
Product Introduction
Zinc Pyrrolidone Carboxylic Acid (Zinc PCA) is a highly bioavailable, water-soluble zinc salt derived from natural L-Pyrrolidone Carboxylic Acid (PCA) and zinc. It is a multifunctional active ingredient widely used in cosmeceuticals, hair care, and dermatological formulations. Unlike inorganic zinc compounds, Zinc PCA combines the sebum-regulating and anti-inflammatory properties of zinc with the natural moisturizing factor (NMF) function of PCA, making it one of the most effective ingredients for acne-prone, oily, and sensitive skin.
INCI Name: Zinc PCA
CAS Number: 15454-75-8
Molecular Formula: C₁₀H₁₂N₂O₆Zn
Appearance: Clear to slightly yellowish solution or white powder (depending on form)
Physical & Chemical Specifications
| Parameter | Specification (Liquid Form) | Specification (Powder Form) |
|---|---|---|
| Appearance | Clear, colorless to pale yellow liquid | White to off-white crystalline powder |
| Zinc Content (Zn) | 1.9% - 2.2% | 20.0% - 22.0% |
| PCA Content | 48% - 52% | 75% - 78% |
| Assay (HPLC) | ≥ 98.0% | ≥ 98.5% |
| pH (10% solution) | 6.0 - 7.5 | 6.0 - 7.5 |
| Heavy Metals (Pb) | ≤ 10 ppm | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm | ≤ 2 ppm |
| Microbial Count (TAMC) | ≤ 100 CFU/g | ≤ 100 CFU/g |
| Yeast & Mold | ≤ 50 CFU/g | ≤ 50 CFU/g |
| Solubility | Fully soluble in water & glycols | Freely soluble in water |
| Storage | Cool, dry, airtight, away from light | Cool, dry, airtight, away from light |
Product Functions
Zinc PCA offers five core mechanisms of action:
- Sebum Regulation (5 α-reductase inhibition): Reduces excessive sebum production by inhibiting 5-alpha reductase enzyme activity, effectively controlling oily skin and scalp.
- Antibacterial & Anti-acne: Exhibits strong bacteriostatic activity against Propionibacterium acnes (P. acnes) and Malassezia fungi.
- Anti-inflammatory: Reduces redness, swelling, and inflammatory markers (IL-1, TNF-α) associated with acne and rosacea.
- Hydration & NMF Function: PCA acts as a potent humectant, attracting moisture into the stratum corneum while zinc prevents transepidermal water loss (TEWL).
- Scalp Health & Anti-dandruff: Normalizes scalp sebum levels and reduces flaking, itching, and dandruff (comparable to low-concentration zinc pyrithione but milder).
Application Areas
| Application | Typical Dosage | Key Benefits |
|---|---|---|
| Facial cleansers & toners | 0.5% - 2.0% | Reduces oiliness, unclogs pores |
| Anti-acne serums & creams | 1.0% - 2.5% | Fights pimples, soothes inflammation |
| Oil-control moisturizers | 0.5% - 1.5% | Mattifying effect, balances sebum |
| Anti-dandruff shampoos | 0.8% - 1.5% | Reduces flakes, itch, and scalp oil |
| Hair tonics & scalp treatments | 0.5% - 1.0% | Prevents hair thinning (by reducing scalp inflammation) |
| Masks & spot treatments | 2.0% - 3.0% | High-concentration acne control |
| Sunscreen & post-sun lotions | 0.2% - 0.5% | Anti-irritant, supports skin barrier |
Manufacturing Process
Our Zinc PCA is produced via a green, two-step synthesis under cGMP guidelines:
- Fermentation & Purification: L-Glutamic acid is enzymatically converted to L-Pyrrolidone Carboxylic Acid (PCA) via bacterial cyclization, followed by activated carbon filtration and ion-exchange purification.
- Complexation (Chelation): High-purity PCA is reacted with zinc bisglycinate or zinc oxide under controlled pH (6.5-7.2) and temperature (60-70°C) to form the stable zinc-PCA chelate.
- Filtration & Stabilization: The solution is microfiltered (0.2 µm) to remove impurities. For powder form, spray drying is applied.
- Quality Testing: Each batch is tested for Zn content, PCA assay, heavy metals, and microbial limits per USP/EP standards.
Reaction Equation: 2 C₅H₇NO₃ (PCA) + ZnO → Zn(C₅H₆NO₃)₂ + H₂O
Why Choose Us
| Criterion | Our Advantage |
|---|---|
| Purity | ≥ 98.5% (HPLC) - Exceeds industry standard (typical 95-97%) |
| Zinc Consistency | Tight control: 20.0-22.0% (powder) vs. market range 18-23% |
| Low Heavy Metals | Pb ≤ 10 ppm, As ≤ 2 ppm - Safe for leave-on cosmetics |
| Production Scale | 20 MT/month capacity - Reliable for bulk orders |
| Certifications | ISO 9001:2015, GMP, Halal, Kosher (upon request) |
| Stability Data | 24-month shelf life with <2% degradation (40°C/75% RH) |
| Technical Support | Free formulation assistance for serums, shampoos, and gels |
| Logistics | Fast shipping via DHL/FedEx; samples ready in 24 hours |
FAQ (Frequently Asked Questions)
Q1: Is Zinc PCA better than Zinc Oxide for acne?
A: For sebum control and deep pore action, yes. Zinc PCA is water-soluble and penetrates the follicle, while Zinc Oxide is a physical particle that sits on the surface. Zinc PCA is preferred for serums and toners; Zinc Oxide is best for sunscreens.
Q2: Can Zinc PCA be used with other active ingredients?
A: Yes. It is compatible with niacinamidess, salicylic acid, hyaluronic acid, and plant extracts. Avoid combining directly with high-pH ingredients (e.g., pure baking soda) or strong cationic surfactants in the same concentrate.
Q3: What is the recommended pH range for final formulations?
A: Optimal final product pH: 5.0 - 6.5 (skin-friendly). Zinc PCA remains stable between pH 4.5 - 7.5.
Q4: Do you offer free samples?
A: Yes. We provide 10g powder or 20ml liquid samples free of charge. Shipping costs may apply for international orders.
Q5: What documentation do you provide?
A: Each shipment includes: COA (Certificate of Analysis), MSDS, Technical Data Sheet (TDS), Allergen Statement, and GMO-free declaration.
Q6: Is Zinc PCA natural?
A: PCA is derived from plant-based glutamic acid (non-GMO corn). Zinc is food-grade mineral. The final chelate is considered natural-derived (ISO 16128 compliant: >0.95 natural origin index).
Q7: Can it be used in clear gel formulations?
A: Absolutely. Zinc PCA is highly water-soluble and will not cause cloudiness or precipitation in carbomers or xanthan gum gels at ≤2% concentration.
Q8: What is the shelf life and storage condition?
A: 24 months in original sealed container. Store below 30°C in a dry, dark place. Do not freeze liquid form.
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