Ascorbic Acid (Vitamin C) CAS 50-81-7: The Gold Standard Antioxidant for Modern Industry
Ascorbic Acid (Vitamin C) CAS 50-81-7 stands as one of the most versatile and commercially significant organic compounds in global chemical trade. As an essential micronutrient and powerful reducing agent, pharmaceutical-grade ascorbic acid powers innovations across nutraceuticals, functional foods, cosmetics, and industrial processing. Our high-purity crystalline powder meets USP, EP, and BP pharmacopoeia standards, delivering consistent potency and stability across diverse formulation requirements.
Technical Highlights & Quality Parameters
1. Pharmaceutical-Grade Purity: With an assay of 99.0–100.5% (on dried basis), our ascorbic acid exceeds compendial specifications for USP/EP/BP grade material. Residual impurities are maintained below 0.1% for heavy metals and <0.05% for iron—critical thresholds for injectable-grade and pediatric formulations.
2. Superior Flow & Compressibility: Engineered through controlled crystallization, our fine crystalline powder exhibits Carr’s Index of <18% and Hausner Ratio <1.20, enabling direct compression tablet manufacturing at speeds exceeding 300,000 tablets per hour without capping or lamination defects.
3. Oxidation Stability: Protected by nitrogen-blanketed packaging and controlled humidity (RH <40%) during fill, our ascorbic acid maintains >99% potency after 24 months under ICH Q1A accelerated stability conditions (40°C/75% RH)—outperforming conventional packaging methods by 15–20%.
4. Low Particle Variability: Laser diffraction PSD analysis confirms D50 between 80–180 μm with span <1.5, ensuring reproducible dissolution profiles across production batches—essential for effervescent tablet and powder sachet applications.
Competitive Comparison
| Parameter | Our Ascorbic Acid | Chinese Competitor A | Indian Supplier | European Source |
|---|
| Assay (HPLC) | 99.0–100.5% | 99.0–100.5% | 98.5–100.5% | 99.0–100.5% |
| Heavy Metals | ≤10 ppm | ≤20 ppm | ≤10 ppm | ≤5 ppm |
| Bulk Density | 0.7–0.9 g/mL | 0.5–0.8 g/mL | 0.6–0.9 g/mL | 0.7–0.9 g/mL |
| 24-Month Potency Retention | >99% | 95–97% | 96–98% | >99% |
| Lead Time (FCL) | 7–10 days | 15–20 days | 21–30 days | 14–21 days |
| Regulatory DMF | US FDA Type II | None | US FDA Type III | CEP/COS |
| Price Index (EXW/kg) | | | | |
Target Customer Scenarios
Nutraceutical Contract Manufacturer — Southeast Asia
A leading ASEAN supplement CMO producing 50M+ effervescent tablets annually switched to our ascorbic acid. Result: 40% reduction in tablet weight variation (RSD from 3.2% to 1.9%) and zero batch rejections for content uniformity over 18 consecutive production campaigns. “The flow consistency is the best we’ve seen—our compression operators no longer need to tweak settings between batches.” — QA Director.
Functional Beverage Formulator — North America
A US-based RTD beverage brand incorporated our ascorbic acid into a vitamin-enhanced sparkling water line. Dissolution time <60 seconds at 5°C without pre-dispersion, with <0.2% sedimentation after 12 months shelf life. The product achieved >$8M first-year revenue and secured placement in 3,200 retail locations. “Cold-water solubility was our biggest challenge with previous suppliers. This material dissolves instantly, even in chilled production.” — R&D Manager.
Cosmetic Active Formulator — Europe
An EU clean-beauty brand adopted our ascorbic acid in a 15% L-ascorbic acid serum with vitamin E and ferulic acid. Stability testing at 25°C/60% RH confirmed >95% active retention at 12 months with no color shift (ΔE < 1.5). The serum became the brand’s top-selling SKU within 6 months of launch. “pH stability and minimal oxidation set this material apart. We finally achieved a clear, stable 15% vitamin C serum.” — Chief Formulator.
Industry Trends
- Immune Health Boom (Post-2025): Global vitamin C market projected to reach $15.8 billion by 2029 at 6.2% CAGR, driven by preventive healthcare and functional food fortification mandates in Asia-Pacific.
- Clean-Label Cosmetics: With EU Cosmetic Regulation 1223/2009 driving natural active ingredient adoption, ascorbic acid demand in skincare is forecast to grow 8.4% annually through 2028.
- Direct Compression Technology: The shift toward DC-grade excipient-free formulations is accelerating—our optimized particle engineering directly addresses this trend, reducing formulation complexity and time-to-market.
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